发明申请
- 专利标题： INHIBITORS OF CATHEPSIN S
- 专利标题（中）： CATHEPSIN的抑制剂
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申请号： US11932679申请日： 2007-10-31
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公开(公告)号： US20080108595A1公开(公告)日： 2008-05-08
- 发明人: Hong Liu , Arnab Chatterjee , David Tully , Phillip Alper , Badry Bursulaya , Jianhua Guo , David Woodmansee , Daniel Mutnick , Donald Karanewsky , Yun He
- 申请人： Hong Liu , Arnab Chatterjee , David Tully , Phillip Alper , Badry Bursulaya , Jianhua Guo , David Woodmansee , Daniel Mutnick , Donald Karanewsky , Yun He
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 主分类号： C07D413/00
- IPC分类号： C07D413/00 ; A61K31/535 ; C07D265/30 ; A61K31/5377 ; A61K31/54 ; C07D279/12 ; C07D241/04 ; A61K31/495 ; A61K31/397 ; C07D205/04
摘要：
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
公开/授权文献
- US07501408B2 Inhibitors of cathepsin S 公开/授权日：2009-03-10
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