发明申请
US20080145365A1 Human and mammalian stem cell-derived neuron survival factors
失效
人和哺乳动物干细胞衍生的神经元存活因子
- 专利标题： Human and mammalian stem cell-derived neuron survival factors
- 专利标题（中）： 人和哺乳动物干细胞衍生的神经元存活因子
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申请号： US10833108申请日： 2004-04-28
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公开(公告)号： US20080145365A1公开(公告)日： 2008-06-19
- 发明人: Tasuku Honjo , Kei Tashiro , Jun Takahashi , Hiroki Toda
- 申请人： Tasuku Honjo , Kei Tashiro , Jun Takahashi , Hiroki Toda
- 专利权人： ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人： ONO PHARMACEUTICAL CO., LTD.
- 优先权： JPP.2001-325189 20011023
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K14/435 ; C07H21/04 ; C12N15/00 ; A61K38/17 ; A61P25/00 ; G01N33/00 ; A61P35/04 ; A61K31/713 ; C12N5/00 ; C12P21/06 ; C07K16/00
摘要：
The present invention relates to human, rat and mouse stem cell-derived neuron survival factor polypeptides (SDNSF), a process for producing them, cDNA encoding SDNSF, a vector comprising the cDNA, host cells transformed by the vector, an antibody against SDNSF, pharmaceutical compositions containing SDNSF or the antibody, a method of assaying SDNSF, a reagent for assaying SDNSF, and a screening method using SDNSF. The polypeptides are effective in the survival of nerve cells and neuronal stem cells, therefore, efficacious in treating injury to the central nerve system and cancer.
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