发明申请
- 专利标题： Cytochrome P450 Oxidase Inhibitors and Uses Thereof
- 专利标题（中）： 细胞色素P450氧化酶抑制剂及其用途
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申请号： US11846600申请日： 2007-08-29
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公开(公告)号： US20080161246A1公开(公告)日： 2008-07-03
- 发明人: Larry L. Klein , Hui-Ju Chen , Ming C. Yeung , Charles A. Flentge , John T. Randolph , Peggy P. Huang , Douglas K. Hutchinson , Dale J. Kempf
- 申请人： Larry L. Klein , Hui-Ju Chen , Ming C. Yeung , Charles A. Flentge , John T. Randolph , Peggy P. Huang , Douglas K. Hutchinson , Dale J. Kempf
- 申请人地址： US IL Abbott Park
- 专利权人： ABBOTT LABORATORIES
- 当前专利权人： ABBOTT LABORATORIES
- 当前专利权人地址： US IL Abbott Park
- 主分类号： A61K38/08
- IPC分类号： A61K38/08 ; C07K7/06 ; A61P31/12
摘要：
The present invention features compounds of formula I or pharmaceutically acceptable salts, solvates or prodrugs thereof, and methods of using the same to inhibit the metabolizing activities of CYP enzymes. The present invention also features methods of using these compounds, salts, solvates or prodrugs to improve the pharmacokinetics of drugs that are metabolized by CYP enzymes.
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