发明申请
- 专利标题： Human anti-B7RP1 Neutralizing Antibodies
- 专利标题（中）： 人类抗B7RP1中和抗体
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申请号： US11458260申请日： 2006-07-18
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公开(公告)号： US20080166352A1公开(公告)日： 2008-07-10
- 发明人: Gerald Siu , Wenyan Shen , Steven Kiyoshi Yoshinaga , Haichun Huang
- 申请人： Gerald Siu , Wenyan Shen , Steven Kiyoshi Yoshinaga , Haichun Huang
- 申请人地址： US CA Thousand Oaks
- 专利权人： AMGEN INC.
- 当前专利权人： AMGEN INC.
- 当前专利权人地址： US CA Thousand Oaks
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; G01N33/53 ; C07H21/00 ; C12N1/00 ; C07K7/06 ; C07K7/08 ; A61K38/08 ; A61K38/10 ; A61P37/00 ; A61P29/00
摘要：
This invention provides antibodies that interact with or bind to human B7 related protein-1 (B7RP1) and antibodies that bind to and neutralize the function of B7RP1 thereby The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing B7RP1 function, and particularly for treating immune disorders (e.g., inappropriate immune response) by administering a pharmaceutically effective amount of anti-B7RP1 antibodies Methods of detecting the amount of B7RP1 in a sample using anti-B7RP1 antibodies are also provided.
公开/授权文献
- US07868140B2 Human anti-B7RP1 neutralizing antibodies 公开/授权日：2011-01-11
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