发明申请
US20080176341A1 Method for Suppressing Intermolecular Nonspecific Interaction and for Intensifying Intermolecular Specific Interaction on Metal Surface
审中-公开
抑制分子间非特异性相互作用和加强金属表面分子间特异性相互作用的方法
- 专利标题： Method for Suppressing Intermolecular Nonspecific Interaction and for Intensifying Intermolecular Specific Interaction on Metal Surface
- 专利标题（中）： 抑制分子间非特异性相互作用和加强金属表面分子间特异性相互作用的方法
-
申请号： US11573868申请日： 2004-08-19
-
公开(公告)号： US20080176341A1公开(公告)日： 2008-07-24
- 发明人: Akito Tanaka , Tomohiro Terada , Tsuruki Tamura , Takaaki Shiyama , Akira Yamazaki , Minoru Furuya , Masayuki Haramura
- 申请人： Akito Tanaka , Tomohiro Terada , Tsuruki Tamura , Takaaki Shiyama , Akira Yamazaki , Minoru Furuya , Masayuki Haramura
- 申请人地址： JP TOKYO
- 专利权人： Reverse Protemics Research Institute Co., Ltd.
- 当前专利权人： Reverse Protemics Research Institute Co., Ltd.
- 当前专利权人地址： JP TOKYO
- 国际申请： PCT/JP04/12218 WO 20040819
- 主分类号： G01N33/553
- IPC分类号： G01N33/553
摘要：
The present invention provides a method of searching for a target molecule for a ligand immobilized on a metal surface or analyzing the interaction between a ligand and a target molecule, characterized in that the immobilization of the ligand on the metal surface via a hydrophilic spacers, and the method eliminates or suppresses a nonspecific interaction that prevents analysis of intermolecular interaction on a metal surface, and can intensify specific intermolecular interactions.