发明申请
- 专利标题： Bone Morphogenic Protein Binding Peptide
- 专利标题（中）： 骨形态发生蛋白结合肽
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申请号： US10587313申请日： 2005-01-28
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公开(公告)号： US20080241108A1公开(公告)日： 2008-10-02
- 发明人: Samuel S. Murray , Keyvan Behnam , Elsa J. Brochmann-Murray
- 申请人： Samuel S. Murray , Keyvan Behnam , Elsa J. Brochmann-Murray
- 国际申请： PCT/US05/02722 WO 20050128
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; C07K7/08 ; A61K38/10 ; G01N33/53 ; C12N1/21 ; A61P19/00 ; C07K16/00 ; C12Q1/68 ; C07H21/04 ; G01N33/68
摘要：
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the over-all osteogenic activity of rgBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
公开/授权文献
- US08188219B2 Bone morphogenic protein binding peptide 公开/授权日：2012-05-29
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