发明申请
- 专利标题： Anti-Radical Agents
- 专利标题（中）： 抗激剂
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申请号： US11792745申请日： 2005-10-24
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公开(公告)号： US20080305055A1公开(公告)日： 2008-12-11
- 发明人: Werner Baschong , Oliver Reich , Sebastien Mongiat
- 申请人： Werner Baschong , Oliver Reich , Sebastien Mongiat
- 优先权： EP04106821.4 20041222
- 国际申请： PCT/EP05/55475 WO 20051024
- 主分类号： A61K8/49
- IPC分类号： A61K8/49 ; A61K31/05 ; A61K31/216 ; A61K31/365 ; A61Q17/00 ; A61P17/00 ; A61K31/165 ; A61K31/53 ; A61K31/445
摘要：
Compounds of the formulae (1), (2) and selected hindered nitroxyl, hydroxylamine and hydroxylamine salt compounds such as the compound of formula (3), wherein Gi is hydrogen; C1-C22alkyl; C1-C22alkylthio; C2-C22alkylthioalkyl; C5-C7cycloalkyl; phenyl; C7-C9phenylalkyl; or SO3M; G2 is C1-C22alkyl; C5-C7cycloalkyl; phenyl; or C7-C9phenylalkyl; E is oxyl or hydroxyl; V is —O—; or —NH—; a is 0 or 1 or 2; b, c and d and g are each independently of one another 0 or 1; e is an integer from 1 to 4; f, m, n and p are each independently of one another an integer from 1 to 3; q is 0 or an integer from 1 to 3; Q, T and G3 are as defined in claim 1; G4 and G5 are each independently of the other hydrogen; or C1-C22alkyl; exhibit marked antiinflammatory action.
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