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    Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin
    1.
    发明申请
    Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin 审中-公开

    公开(公告)号：US20080279794A1

    公开(公告)日：2008-11-13

    申请号：US12214998

    申请日：2008-06-24

    申请人： Werner Baschong ,  Marcel Schnyder

    发明人： Werner Baschong ,  Marcel Schnyder

    IPC分类号： A61K8/49 ,  A61Q19/02 ,  A61Q17/04

    CPC分类号： A61Q19/02 ,  A61K8/347

    摘要： The use of (a) hydroxydiphenyl ether compounds of formula  wherein R1, R2 and R3 are each independently of the others hydrogen; hydroxy; C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; C1-C20alkoxy; C1-C6alkylcarbonyl; phenyl; or phenyl-C1-C3alkyl; R4 is hydrogen, C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C1-C3alkyl; carboxyallyl; C2-C20alkenyl; C1-C6alkylcarbonyl; C1-C3alkylcarbonyl-C1-C3alkyl; phenyl; or phenyl-C1-C3alkyl; and R5 is hydrogen; C1-C20alkoxy; or C1-C6alkylcarbonyl; as melanogenesis inhibitors and for lightening the skin.

    Glucan Compositions
    4.
    发明申请
    Glucan Compositions 审中-公开
    葡聚糖组合物

    公开(公告)号：US20090156563A1

    公开(公告)日：2009-06-18

    申请号：US12085271

    申请日：2006-11-20

    申请人： Werner Baschong ,  Sebastien Mongiat ,  Dietmar Ochs

    发明人： Werner Baschong ,  Sebastien Mongiat ,  Dietmar Ochs

    IPC分类号： A61K31/60 ,  A61P17/00

    CPC分类号： A61Q11/00 ,  A61K8/345 ,  A61K8/347 ,  A61K8/365 ,  A61K8/43 ,  A61K8/73 ,  A61K31/716 ,  A61Q1/10 ,  A61Q1/14 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/00 ,  A61Q19/08

    摘要： A cosmetic or pharmaceutical composition is provided comprising: a) 0.001 to less than 0.2% by weight, based on the weight of the total composition, of a scleroglucan having a mean molecular weight of 1×106 to 12×106; b) a cosmetically or pharmaceutically acceptable carrier; and, optionally, c) lactic acid, a lactate and/or pentanediol. The composition shows advantageous effects, such as moisturization of skin or mucosa, and has an antiaging and revitalizing effect on the skin. When combined with a certain bactericide as explained in claim 1, compositions containing native polysaccharides of the glucan class in general, especially of the scleroglucan as of component a), are well suitable to reduce the number of bacteria in mucosal or oral environments and minimise adhesion, while retaining a pleasant feeling on the mucosa or gingiva. Plaque thus can be efficiently prevented or removed.

    摘要翻译： 提供了一种化妆品或药物组合物，其包含：a）以总组合物的重量计0.001至小于0.2重量％的平均分子量为1×10 6至12×10 6的硬皮葡聚糖; b）美容或药学上可接受的载体; 和任选地，c）乳酸，乳酸盐和/或戊二醇。 该组合物显示出有益的效果，例如皮肤或粘膜的保湿，并且对皮肤具有抗衰老和振兴作用。 当与根据权利要求1所述的某种杀菌剂组合时，含有葡聚糖类的天然多糖的组合物通常特别是组分a）的硬化葡聚糖是非常适合于减少粘膜或口腔环境中细菌的数量并最小化粘附 同时保持对粘膜或牙龈的愉悦感。 因此可以有效地防止或去除斑块。

    Protection of Oxidizable Agents
    6.
    发明申请
    Protection of Oxidizable Agents 审中-公开
    氧化剂的保护

    公开(公告)号：US20090258041A1

    公开(公告)日：2009-10-15

    申请号：US12083557

    申请日：2006-06-21

    申请人： Sebastien Mongiat ,  Werner Baschong ,  Bernd Herzog

    发明人： Sebastien Mongiat ,  Werner Baschong ,  Bernd Herzog

    IPC分类号： A61K8/02 ,  A61P17/02

    CPC分类号： A61K31/05 ,  A61K8/11 ,  A61K8/14 ,  A61K8/347 ,  A61K8/37 ,  A61K8/375 ,  A61K8/42 ,  A61K8/46 ,  A61K8/466 ,  A61K8/4926 ,  A61K8/4966 ,  A61K8/4973 ,  A61K8/553 ,  A61K8/671 ,  A61K8/676 ,  A61K31/222 ,  A61K31/255 ,  A61K31/34 ,  A61K31/445 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/522 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10

    摘要： Formulations for cosmetical or pharmaceutical use contain an antioxidant in encapsulated form and a cosmetically or pharmaceutically acceptable carrier. The antioxidant is selected from carbon bridged hindered phenoles, ester bridged hindered phenoles, amide bridged hindered phenoles, lactones of hindered phenoles, sterically hindered oxylamines and sterically hindered hydroxylamines. The encapsulated antioxidant is of high activity and suitable to protect a further active ingredient, e.g. oxidizable natural substances, vitamins, fragrances, and extracts from plants fungi, algae or animals, from premature degradation, especially when coencapsulated together with the ingredient. The formulations are useful inter alia for the preparation of a cosmetical or pharmaceutical skin care or skin delivery formulation, injectable solution, infusion solution, eye drop, drinking solution, a dietary or enriched food, an oral care formulation, drinking gargles, in-halants, or as a food additive.

    摘要翻译： 化妆品或药物用途的制剂含有包封形式的抗氧化剂和化妆品或药学上可接受的载体。 抗氧化剂选自碳桥接的受阻酚，酯桥接的受阻酚，酰胺桥接的受阻酚，受阻酚的内酯，空间位阻的羟胺和空间位阻羟胺。 包封的抗氧化剂具有高活性并且适于保护另外的活性成分，例如， 可氧化的天然物质，维生素，香料，以及来自植物真菌，藻类或动物的提取物，过早降解，特别是当与成分一起胶囊时。 该制剂尤其用于制备美容或药物皮肤护理或皮肤递送制剂，可注射溶液，输注溶液，滴眼剂，饮用溶液，饮食或富含食物，口腔护理制剂，饮用漱口剂，漱口剂 ，或作为食品添加剂。

    Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin
    8.
    发明申请
    Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin 审中-公开
    使用卤代羟基二苯醚化合物治疗皮肤

    公开(公告)号：US20060216252A1

    公开(公告)日：2006-09-28

    申请号：US10564712

    申请日：2004-07-07

    申请人： Werner Baschong ,  Marcel Schnyder

    发明人： Werner Baschong ,  Marcel Schnyder

    IPC分类号： A61K8/46 ,  A61K8/34

    CPC分类号： A61Q19/02 ,  A61K8/347

    摘要： The use of hydroxydiphenyl ether compounds of formula (I), wherein R1, R2 and R3 are each independently of the others hydrogen; hydroxy; C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; C1-C20alkoxy; C1-C6alkylcarbonyl; phenyl; or phenyl-C1-C3alkyl; R4 is hydrogen, C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C1-C3alkyl; carboxyallyl; C2-C20alkenyl; C1-C6alkylcarbonyl; C1-C3alkylcarbonyl-C1-C3alkyl; phenyl; or phenyl-C1-C3alkyl; and R5 is hydrogen; C1-C20alkoxy; or C1-C6alkylcarbonyl; as melanogenesis inhibitors and for lightening the skin.

    摘要翻译： 式（I）的羟基二苯醚化合物（其中R 1，R 2和R 3）各自独立地为氢; 羟基; C 1 -C 20烷基; C 1 -C 20烷基; 羟基取代的C 1 -C 20烷基; C 5 -C 7环烷基; C 1 -C 20烷氧基; C 1 -C 6烷基羰基; C 1 -C 6烷基羰基; 苯基; 或苯基-C 1 -C 3烷基; R 4是氢，C 1 -C 20烷基; 羟基取代的C 1 -C 20烷基; C 5 -C 7环烷基; 羟基; 甲酰基 丙酮; 烯丙基 羧基; 羧基-C 1 -C 3烷基; 羧基 C 2 -C 20链烯基; C 1 -C 6烷基羰基; C 1 -C 6烷基羰基; C 1 -C 3烷基羰基-C 1 -C 3烷基; C 1 -C 3烷基; C 1 -C 3烷基; 苯基; 或苯基-C 1 -C 3烷基; 并且R 5是氢; C 1 -C 20烷氧基; 或C 1 -C 6烷基羰基; 作为黑素生成抑制剂和减轻皮肤。