发明申请
US20080305098A1 Recombinant Polypeptides and Methods for Detecting and/or Quantifying Autoantibodies Against Tsh Receptor
审中-公开
重组多肽和用于检测和/或定量针对Tsh受体的自身抗体的方法
- 专利标题： Recombinant Polypeptides and Methods for Detecting and/or Quantifying Autoantibodies Against Tsh Receptor
- 专利标题（中）： 重组多肽和用于检测和/或定量针对Tsh受体的自身抗体的方法
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申请号： US12094533申请日： 2006-11-21
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公开(公告)号： US20080305098A1公开(公告)日： 2008-12-11
- 发明人: Steve Fenning , Xiaoping Yang , Andreas Dreusch , Wolfgang Rudy
- 申请人： Steve Fenning , Xiaoping Yang , Andreas Dreusch , Wolfgang Rudy
- 申请人地址： DE Kirchzarten DE Karlsruhe
- 专利权人： DR. FENNING BIOMED GMBH,MICROMOL GMBH
- 当前专利权人： DR. FENNING BIOMED GMBH,MICROMOL GMBH
- 当前专利权人地址： DE Kirchzarten DE Karlsruhe
- 国际申请： PCT/IB2006/003394 WO 20061121
- 主分类号： A61K38/43
- IPC分类号： A61K38/43 ; C07K16/18 ; C12N9/10 ; C12N9/24 ; C12N15/11 ; A61P43/00 ; C12N15/00 ; C12N1/20 ; G01N33/53
摘要：
The present invention relates to unglycosylated isolated and purified recombinant polypeptides comprising a fusion protein able to bind to autoantibodies produced in response to an autoimmune disease associated with an immune reaction to a TSH-receptor (TSHR). Also disclosed are methods of detecting and/or quantifying such autoantibodies using the isolated and purified recombinant polypeptides and respective kits.
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