发明申请
- 专利标题： MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
- 专利标题（中）： ATP结合蛋白转运蛋白的调节剂
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申请号： US12114935申请日： 2008-05-05
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公开(公告)号： US20080306062A1公开(公告)日： 2008-12-11
- 发明人: Sara S. Hadida Ruah , Matthew Hamilton , Mark Miller , Peter D.J. Grootenhuis , Brian Bear , Jason McCartney , Jinglan Zhou
- 申请人： Sara S. Hadida Ruah , Matthew Hamilton , Mark Miller , Peter D.J. Grootenhuis , Brian Bear , Jason McCartney , Jinglan Zhou
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D405/12 ; A61K31/443 ; A61K31/4545 ; C07K14/47 ; G01N33/68 ; C07D405/14 ; A61K31/501 ; C07D413/14
摘要：
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
公开/授权文献
- US08993600B2 Modulators of ATP-binding cassette transporters 公开/授权日：2015-03-31
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