发明申请
- 专利标题： PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME
- 专利标题（中）： 苯氧基衍生物及其结晶及其制备方法
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申请号： US12031568申请日： 2008-02-14
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公开(公告)号： US20080318924A1公开(公告)日： 2008-12-25
- 发明人: Tomohiro MATSUSHIMA , Shuji Shirotori , Keiko Takahashi , Atsushi Kamada , Kazunori Wakasugi , Takahisa Sakaguchi
- 申请人： Tomohiro MATSUSHIMA , Shuji Shirotori , Keiko Takahashi , Atsushi Kamada , Kazunori Wakasugi , Takahisa Sakaguchi
- 申请人地址： JP Tokyo
- 专利权人： Eisai R&D Management Co., Ltd
- 当前专利权人： Eisai R&D Management Co., Ltd
- 当前专利权人地址： JP Tokyo
- 优先权： JP2007-036690 20070216
- 主分类号： A61K31/4427
- IPC分类号： A61K31/4427 ; C07D401/14 ; C07D401/12 ; A61P35/00 ; A61K31/496
摘要：
The invention provides acid addition salts of the compounds represented by formula (1) or (2), or crystals thereof, and processes for preparing the same. The salts or crystals have HGFR inhibitory activity and excellent physical properties (solubility, safety, etc.) and are therefore useful as anti-tumor agents, angiogenesis inhibitors and inhibitors for metastasis for a various types of tumor.
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