发明申请
- 专利标题: Compounds and Methods of Use Thereof
- 专利标题(中): 化合物及其使用方法
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申请号: US11718286申请日: 2005-10-27
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公开(公告)号: US20080319044A1公开(公告)日: 2008-12-25
- 发明人: John R. Didsbury , Tatyana A. Dyakonov , Simon N. Haydar , Michael L. Jones , Francine F. Li , Christopher J. Markworth , Jessymol Mathew , Frank J. Schoenen , Jan J. Scicinski , David Middlemiss
- 申请人: John R. Didsbury , Tatyana A. Dyakonov , Simon N. Haydar , Michael L. Jones , Francine F. Li , Christopher J. Markworth , Jessymol Mathew , Frank J. Schoenen , Jan J. Scicinski , David Middlemiss
- 申请人地址: US NC Durham
- 专利权人: NUADA, LLC
- 当前专利权人: NUADA, LLC
- 当前专利权人地址: US NC Durham
- 国际申请: PCT/US05/39204 WO 20051027
- 主分类号: A61K31/404
- IPC分类号: A61K31/404 ; C07D209/04 ; A61P1/00 ; A61P19/02 ; A61P17/06 ; A61P25/28 ; A61P9/00 ; A61P3/10 ; A61P35/00 ; A61P9/12 ; A61P15/10
摘要:
Indole boronic acid compounds, and analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) in a subject in need thereof.