发明申请
- 专利标题： Thio-Substituted Biarylmethanesulfinyl Derivatives
- 专利标题（中）： 硫取代的二芳基甲亚磺酰基衍生物
-
申请号： US12199167申请日： 2008-08-27
-
公开(公告)号： US20090062284A1公开(公告)日： 2009-03-05
- 发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , Marie-Edith Gourdel , Greg A. Hostetler , Mohamed Iqbal , Brigitte Lesur , Philippe Louvet , Eric Riguet , Dominique Schweizer , Christophe Yue
- 申请人： Edward R. Bacon , Sankar Chatterjee , Derek Dunn , Marie-Edith Gourdel , Greg A. Hostetler , Mohamed Iqbal , Brigitte Lesur , Philippe Louvet , Eric Riguet , Dominique Schweizer , Christophe Yue
- 申请人地址： US PA Frazer
- 专利权人： Cephalon, Inc.
- 当前专利权人： Cephalon, Inc.
- 当前专利权人地址： US PA Frazer
- 优先权： EP04290982.0 20040413
- 主分类号： A61K31/381
- IPC分类号： A61K31/381 ; C07D333/24 ; C07D307/54 ; C07D409/12 ; C07D405/12 ; C07D401/12 ; C07D413/12 ; C07D209/44 ; C07C235/72 ; A61K31/496 ; A61K31/40 ; A61K31/4025 ; A61K31/5377 ; A61P25/00
摘要：
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted biaryl-methanesulfinyl acetamides of Formula (I): wherein Ar, Y, R1, R2, R4, R5, q and x are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder; Parkinson's disease; Alzheimer's disease; attention deficit disorder; attention deficit hyperactivity disorder; depression; or fatigue associated with a neurological disease; as well as the promotion of wakefulness.
公开/授权文献
- US07981907B2 Thio-substituted biarylmethanesulfinyl derivatives 公开/授权日：2011-07-19
信息查询
