发明申请
- 专利标题: NOVEL ANTIBACTERIAL COMPOUNDS
- 专利标题(中): 新型抗菌化合物
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申请号: US12226403申请日: 2007-04-10
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公开(公告)号: US20090076094A1公开(公告)日: 2009-03-19
- 发明人: Girish Badrinath Mahajan , Saji David George , Prafull Vasant Ranadive , Prabhu Dutt Satyanarayan Mishra , Sreekumar Sankaranarayanan Eyyammadichiyil , Rajan Mukund Panshikar , Satish Namdeo Sawant , Sridevi Krishna , Meenakshi Sivakumar , Koteppa Pari , Becky Mary Thomas , Zarine Eruch Patel , Ram Vishwakarma , Chandrakant Govind Naik , Lisette D'Souza , Prabha Devi
- 申请人: Girish Badrinath Mahajan , Saji David George , Prafull Vasant Ranadive , Prabhu Dutt Satyanarayan Mishra , Sreekumar Sankaranarayanan Eyyammadichiyil , Rajan Mukund Panshikar , Satish Namdeo Sawant , Sridevi Krishna , Meenakshi Sivakumar , Koteppa Pari , Becky Mary Thomas , Zarine Eruch Patel , Ram Vishwakarma , Chandrakant Govind Naik , Lisette D'Souza , Prabha Devi
- 申请人地址: IN Mumbai IN New Delhi
- 专利权人: PIRAMAL LIFE SCIENCES LIMITED,COUNCIL OF SCIENTIFIC AND INDUSTRIAL
- 当前专利权人: PIRAMAL LIFE SCIENCES LIMITED,COUNCIL OF SCIENTIFIC AND INDUSTRIAL
- 当前专利权人地址: IN Mumbai IN New Delhi
- 优先权: IN607/MUM/2006 20060418
- 国际申请: PCT/IB2007/051268 WO 20070410
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; C07D417/14 ; A61P31/04 ; C12P17/16
摘要:
This invention relates to a novel purified compound PM181104, of formula: of molecular weight 1514 and molecular formula C69H66N18O13S5; which is obtained by fermentation of the microorganism belonging to Kocuria species (ZMA B-1/MTCC 5269). The invention includes all stereoisomeric forms and all tautomeric forms of the compound PM181104 and pharmaceutically acceptable salts and derivatives such as esters and ethers. The present invention further relates to processes for the production of the novel antibacterial compound(s), to the production of the microorganism belonging to Kocuria species (ZMA B-1/MTCC 5269), and to pharmaceutical compositions containing the novel compound(s) as an active ingredient and its/their use in medicines for treatment and prevention of diseases caused by bacterial infections.
公开/授权文献
- US08003602B2 Antibacterial compounds 公开/授权日:2011-08-23
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