发明申请
- 专利标题: Amylolytic Enzyme Variants
- 专利标题(中): 淀粉分解酶变体
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申请号: US12208425申请日: 2008-09-11
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公开(公告)号: US20090142803A1公开(公告)日: 2009-06-04
- 发明人: Joel Robert Cherry , Allan Svendsen , Carsten Denmark Andersen , Lars Beier , Torben Peter Frandsen , Thomas Schafer
- 申请人: Joel Robert Cherry , Allan Svendsen , Carsten Denmark Andersen , Lars Beier , Torben Peter Frandsen , Thomas Schafer
- 申请人地址: DK Bagsvaerd
- 专利权人: Novozymes A/S
- 当前专利权人: Novozymes A/S
- 当前专利权人地址: DK Bagsvaerd
- 优先权: DK199800269 19980227; DK199800273 19980227
- 主分类号: C12N9/10
- IPC分类号: C12N9/10 ; C12P21/00
摘要:
The inventors have discovered some striking, and not previously predicted structural similarities and differences between the structure of Novamyl and the reported structures of CGTases, and based on this they have constructed variants of maltogenic alpha-amylase having CGTase activity and variants of CGTase having maltogenic alpha-amylase activity. Further, on the basis of sequence homology between Novamyl® and CGTases, the inventors have constructed hybrid enzymes with one or more improvements to specific properties of the parent enzymes, using recombinant DNA methodology.
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