发明申请
US20090181966A1 PGD2 receptor antagonists for the treatment of inflammatory diseases
审中-公开
PGD2受体拮抗剂治疗炎性疾病
- 专利标题： PGD2 receptor antagonists for the treatment of inflammatory diseases
- 专利标题（中）： PGD2受体拮抗剂治疗炎性疾病
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申请号： US12321910申请日： 2009-01-27
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公开(公告)号： US20090181966A1公开(公告)日： 2009-07-16
- 发明人: Shomir Ghosh , Amy M. Elder , Kenneth G. Carson , Kevin T. Sprott , Sean J. Harrison , Frederick A. Hicks , Christelle C. Renou , Dominic Reynolds
- 申请人： Shomir Ghosh , Amy M. Elder , Kenneth G. Carson , Kevin T. Sprott , Sean J. Harrison , Frederick A. Hicks , Christelle C. Renou , Dominic Reynolds
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; C07D215/42 ; A61K31/5377 ; A61P37/08 ; C07D413/06
摘要：
Disclosed herein are compounds represented by Structural Formula (I) and (I-A): Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2, or simply “CRTH2” for the treatment of inflammatory disorders. The variables in Structural Formula (I) and (I-A) are defined herein.
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