发明申请
- 专利标题: SYSTEMS AND METHODS FOR Ex vivo LUNG CARE
- 专利标题(中): 用于离体肺保健的系统和方法
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申请号: US12099728申请日: 2008-04-08
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公开(公告)号: US20090197325A1公开(公告)日: 2009-08-06
- 发明人: Robert FISHMAN , Robert HAVENER , Ihab Abdel FATTAH , Anas ABDELAZIM , Scott NEWELL , Tom BISHOP , Tamer KHAYAL , Stanley KYI , Ron TAYLOR , Doug HARRIOTT , Matthew DE REMER , Paul MURRAY , John SULLIVAN , Mark ANDERSON , Richard BRINGHAM , Michael VAN DRIEL , Waleed Hassanein
- 申请人: Robert FISHMAN , Robert HAVENER , Ihab Abdel FATTAH , Anas ABDELAZIM , Scott NEWELL , Tom BISHOP , Tamer KHAYAL , Stanley KYI , Ron TAYLOR , Doug HARRIOTT , Matthew DE REMER , Paul MURRAY , John SULLIVAN , Mark ANDERSON , Richard BRINGHAM , Michael VAN DRIEL , Waleed Hassanein
- 专利权人: TRANSMEDICS, INC
- 当前专利权人: TRANSMEDICS, INC
- 主分类号: A01N1/02
- IPC分类号: A01N1/02
摘要:
Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.
公开/授权文献
- US09814230B2 Systems and methods for ex vivo lung care 公开/授权日:2017-11-14