发明申请
US20090209582A1 Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
有权
苯并咪唑 - 甲酰胺化合物作为5-ht4受体激动剂
- 专利标题: Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
- 专利标题(中): 苯并咪唑 - 甲酰胺化合物作为5-ht4受体激动剂
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申请号: US11920817申请日: 2006-05-24
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公开(公告)号: US20090209582A1公开(公告)日: 2009-08-20
- 发明人: Robert Murray McKinnell , Roland Gendron , Lan Jiang , Seok-ki Choi , Daniel D. Long , Paul R. Fatheree , Daniel Marquess , Sean Dalziel , Kirsten M. Phizackerley
- 申请人: Robert Murray McKinnell , Roland Gendron , Lan Jiang , Seok-ki Choi , Daniel D. Long , Paul R. Fatheree , Daniel Marquess , Sean Dalziel , Kirsten M. Phizackerley
- 国际申请: PCT/US2006/020085 WO 20060524
- 主分类号: A61K31/4545
- IPC分类号: A61K31/4545 ; C07D401/14 ; A61P1/00
摘要:
The invention relates to benzimidazole-carboxamide 5-HT4 receptor agonist compounds of formula (I) wherein R1 and X are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds. The invention further relates to crystalline forms of a compound of formula (I).
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