发明申请
- 专利标题: OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION
- 专利标题(中): 奥沙唑化合物和药物组合物
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申请号: US12090951申请日: 2006-11-14
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公开(公告)号: US20090221586A1公开(公告)日: 2009-09-03
- 发明人: Minoru Okada , Masaya Kato , Norifumi Sato , Tetsuyuki Uno , Hideki Kitagaki , Junpei Haruta , Hidetaka Hiyama , Tomonori Shibata
- 申请人: Minoru Okada , Masaya Kato , Norifumi Sato , Tetsuyuki Uno , Hideki Kitagaki , Junpei Haruta , Hidetaka Hiyama , Tomonori Shibata
- 申请人地址: JP Tokyo
- 专利权人: OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人: OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2005-330590 20051115
- 国际申请: PCT/JP2006/323066 WO 20061114
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/497 ; A61K31/4439 ; A61K31/421 ; C07D413/12 ; C07D263/34
摘要:
The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by —Y1-A1- or —Y2—C(═O)— wherein Y1 is a group such as —C(═O)—, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.
公开/授权文献
- US08637559B2 Oxazole compound and pharmaceutical composition 公开/授权日:2014-01-28
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