发明申请
- 专利标题： Botulinum Neurotoxin a Protein Receptor and Uses Thereof
- 专利标题（中）： 肉毒杆菌神经毒素蛋白受体及其用途
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申请号： US12084074申请日： 2006-10-30
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公开(公告)号： US20090252722A1公开(公告)日： 2009-10-08
- 发明人: Stefan Mahrhold , Johannes Wilhelm Bigalke , Andreas Rummel , Thomas Binz
- 申请人： Stefan Mahrhold , Johannes Wilhelm Bigalke , Andreas Rummel , Thomas Binz
- 优先权： DE102005051789.7 20051028
- 国际申请： PCT/EP2006/010420 WO 20061030
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K14/00 ; C07H21/04 ; C12N15/63 ; C12N5/10 ; C12P21/00 ; C07K16/00 ; A61K38/16 ; A61K31/7088 ; G01N33/53 ; A61P43/00
摘要：
The invention relates to a polypeptide comprising an amino acid sequence, at least 70 percent of which are identical to the amino acid sequence of the synaptic vesicle glycoprotein of homo sapiens. Said polypeptide binds the HC fragment of botulinum neurotoxin A provided that the polypeptide is not the synaptic vesicle glycoprotein 2C of homo sapiens.
公开/授权文献
- US08476024B2 Botulinum neurotoxin a protein receptor and uses thereof 公开/授权日：2013-07-02