发明申请
- 专利标题： BCMA POLYPEPTIDES AND USES THEREOF
- 专利标题（中）： BCMA聚合物及其用途
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申请号： US12405018申请日： 2009-03-16
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公开(公告)号： US20090297504A1公开(公告)日： 2009-12-03
- 发明人: Robert F. Kelley , Darshana Ramesh Patel
- 申请人： Robert F. Kelley , Darshana Ramesh Patel
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C07H21/04 ; C12N15/63 ; C12N5/10 ; C12P21/02 ; G01N33/53 ; A61P35/00 ; A61P37/00
摘要：
The present invention relates to polypeptides that inhibit APRIL and/or BAFF binding to BCMA, nucleic acid molecules encoding the polypeptides, and compositions comprising the polypeptides. The present invention also relates to methods for treating an immune-related disease or cancer using the polypeptides and compositions of the invention. The present invention also relates to methods for identifying inhibitors of APRIL/BAFF binding to BCMA and APRIL/BAFF signaling.
公开/授权文献
- US08105603B2 Polypeptides that bind APRIL 公开/授权日：2012-01-31
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