发明申请
- 专利标题: TRANSGLUTAMINASE VARIANTS WITH IMPROVED SPECIFICITY
- 专利标题(中): 具有改善特异性的转谷氨酰胺酶变体
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申请号: US12310275申请日: 2007-08-17
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公开(公告)号: US20090318349A1公开(公告)日: 2009-12-24
- 发明人: Zhixiang Hu , Xin Zhao , Jianhua Wang , Chih-Chuan Chang , Leif Norskov-Lauritsen
- 申请人: Zhixiang Hu , Xin Zhao , Jianhua Wang , Chih-Chuan Chang , Leif Norskov-Lauritsen
- 申请人地址: CH Zurich
- 专利权人: Novo Nordisk Health Care AG
- 当前专利权人: Novo Nordisk Health Care AG
- 当前专利权人地址: CH Zurich
- 优先权: EPPCT/EP2006/065439 20060818; EP07102885.6 20070222; EP07102886.4 20070222
- 国际申请: PCT/EP2007/058571 WO 20070817
- 主分类号: A61K38/27
- IPC分类号: A61K38/27 ; C12N9/00 ; C07K14/195 ; C07H21/00 ; C12N15/63 ; C07K14/61 ; C12N1/19 ; C12N1/15 ; C12N1/21
摘要:
Variants of transglutaminase from Streptoverticillium ladakanum, which variants have improved selectivity for Gln-141 of human growth hormone are provided.
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