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公开(公告)号:US20090318349A1
公开(公告)日:2009-12-24
申请号:US12310275
申请日:2007-08-17
IPC分类号: A61K38/27 , C12N9/00 , C07K14/195 , C07H21/00 , C12N15/63 , C07K14/61 , C12N1/19 , C12N1/15 , C12N1/21
CPC分类号: C12N9/1044 , A61K47/60 , C07K14/61
摘要: Variants of transglutaminase from Streptoverticillium ladakanum, which variants have improved selectivity for Gln-141 of human growth hormone are provided.
摘要翻译: 提供了来自链霉菌(Streptoverticillium ladakanum)的转谷氨酰胺酶的变体,其变体对人生长激素的Gln-141具有改善的选择性。
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公开(公告)号:US20070048785A1
公开(公告)日:2007-03-01
申请号:US11149025
申请日:2005-06-09
申请人: Laura Lin , Kevin Parris , Amy Sze Tam , Xiang-Yang Tan , Tania Shane , John Dumas , James Wilhelm , Mark Stahl , Lidia Mosyak , Zhixiang Hu
发明人: Laura Lin , Kevin Parris , Amy Sze Tam , Xiang-Yang Tan , Tania Shane , John Dumas , James Wilhelm , Mark Stahl , Lidia Mosyak , Zhixiang Hu
CPC分类号: C07K16/244 , A61K2039/505 , C07K2317/24 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: Anti-IL-13 antibodies, crystals of anti-IL-13 antibodies, IL-13 polypeptide/anti-IL-13 antibody complexes, crystals of IL-13 polypeptide/anti-IL-13 antibody complexes, IL-13Rα1 polypeptide/IL-13 polypeptide/anti-IL-13 antibody complexes, crystals of IL-13Rα1 polypeptide/IL-13 polypeptide/anti-IL-13 antibody complexes, and related methods and software systems are disclosed.
摘要翻译: 抗IL-13抗体,抗IL-13抗体晶体,IL-13多肽/抗IL-13抗体复合物,IL-13多肽/抗IL-13抗体复合物的结晶,IL-13Rα1多肽/ IL -13多肽/抗IL-13抗体复合物,IL-13Rα1多肽/ IL-13多肽/抗IL-13抗体复合物的晶体,以及相关方法和软件系统。
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