发明申请
- 专利标题: TYROSINE DERIVATIVE
- 专利标题(中): 酪氨酸衍生物
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申请号: US12545671申请日: 2009-08-21
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公开(公告)号: US20090325962A1公开(公告)日: 2009-12-31
- 发明人: David Y. Jackson , Frederick C. Sailes , Daniel P. Sutherlin
- 申请人: David Y. Jackson , Frederick C. Sailes , Daniel P. Sutherlin
- 申请人地址: US CA South San Francisco
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: A61K31/5375
- IPC分类号: A61K31/5375 ; C07C271/40 ; A61K31/27 ; C07D263/58 ; A61K31/421 ; C07D217/00 ; A61K31/47 ; C07D215/00 ; C07D265/30 ; C07D241/04 ; A61K31/495 ; C07C229/00 ; A61K31/195 ; A61P19/02 ; A61P11/06 ; A61P17/00 ; A61P1/00
摘要:
The compounds of the invention are inhibitors of alpha4 containing integrin-mediated binding to ligands such as VCAM-1 and MAdCAM.