Invention Application
US20100047846A1 ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G PROTEIN-COUPLED RECEPTORS
审中-公开
人G蛋白偶联受体的内源性和非内源性版本
- Patent Title: ENDOGENOUS AND NON-ENDOGENOUS VERSIONS OF HUMAN G PROTEIN-COUPLED RECEPTORS
- Patent Title (中): 人G蛋白偶联受体的内源性和非内源性版本
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Application No.: US12536371Application Date: 2009-08-05
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Publication No.: US20100047846A1Publication Date: 2010-02-25
- Inventor: Ruoping Chen , Huong T. Dang , Kevin P. Lowitz
- Applicant: Ruoping Chen , Huong T. Dang , Kevin P. Lowitz
- Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee: Arena Pharmaceuticals, Inc.
- Main IPC: C12Q1/02
- IPC: C12Q1/02 ; C07H21/04 ; C12N15/63 ; C12N5/00 ; C12N15/00 ; C07K14/705
Abstract:
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown (“orphan GPCR receptors”), and most particularly to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.
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