Invention Application
- Patent Title: METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING DISEASES
- Patent Title (中): 用于治疗和诊断疾病的方法和组合
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Application No.: US12504826Application Date: 2009-07-17
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Publication No.: US20100061977A1Publication Date: 2010-03-11
- Inventor: Steve RUBEN , Karen VAN ORDEN , Candy N. LEE , Tao HE , Mehdi MESRI , Elizabeth G. JOSELOFF , Paul MOORE , Katherine MCKINNON , Bruno DOMON
- Applicant: Steve RUBEN , Karen VAN ORDEN , Candy N. LEE , Tao HE , Mehdi MESRI , Elizabeth G. JOSELOFF , Paul MOORE , Katherine MCKINNON , Bruno DOMON
- Applicant Address: US CA Alameda
- Assignee: CELERA CORPORATION
- Current Assignee: CELERA CORPORATION
- Current Assignee Address: US CA Alameda
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K14/00 ; A61K38/16 ; C07H21/00 ; C07H21/02 ; C07K16/18 ; C12N5/16 ; C12N5/00 ; G01N33/53 ; C12N7/01 ; A61P35/00

Abstract:
Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.
Public/Granted literature
- US08110373B2 Methods and compositions for treating and diagnosing diseases Public/Granted day:2012-02-07
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