发明申请
US20100062009A9 NOVEL STROMAL CELL-DERIVED FACTOR-1 POLYPEPTIDES, POLYNUCLEOTIDES, MODULATORS THEREOF AND METHODS OF USE
有权
新型结晶细胞衍生因子-1多肽，多核苷酸，其调节剂及其使用方法
- 专利标题： NOVEL STROMAL CELL-DERIVED FACTOR-1 POLYPEPTIDES, POLYNUCLEOTIDES, MODULATORS THEREOF AND METHODS OF USE
- 专利标题（中）： 新型结晶细胞衍生因子-1多肽，多核苷酸，其调节剂及其使用方法
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申请号： US11587651申请日： 2005-04-29
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公开(公告)号： US20100062009A9公开(公告)日： 2010-03-11
- 发明人: Keting Chu , Lewis T. Williams , Justin G.P. Wong , Kevin Hestir , Amy L. Tsui Collins , Ernestine Lee
- 申请人： Keting Chu , Lewis T. Williams , Justin G.P. Wong , Kevin Hestir , Amy L. Tsui Collins , Ernestine Lee
- 申请人地址： US CA San Francisco
- 专利权人： FIVE PRIME THERAPEUTICS, INC.
- 当前专利权人： FIVE PRIME THERAPEUTICS, INC.
- 当前专利权人地址： US CA San Francisco
- 国际申请： PCT/US2005/014963 WO 20050429
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C12N15/11 ; C07K14/00 ; C12N15/87 ; C12P21/04 ; A61P31/00 ; C12N5/06 ; G01N33/566 ; A61K38/00 ; A61K35/12
摘要：
Disclosed herein is a newly identified SDF-1 splice variant molecule, its polypeptide sequence, and the polynucleotides encoding the polypeptide sequence, and active fragments thereof. Also provided is a procedure for producing such polypeptides by recombinant techniques employing, for example, vectors and host cells. Also disclosed are methods for utilizing such polypeptides and modulators thereof for the treatment of diseases, including cancer, immune diseases, infectious diseases, and ischemic diseases.
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