发明申请
- 专利标题： CONDENSED TETRAHYDROQUINOLINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES
- 专利标题（中）： 浓缩四氢喹啉衍生物及其用于医疗用途
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申请号： US12523031申请日： 2008-01-15
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公开(公告)号： US20100063055A1公开(公告)日： 2010-03-11
- 发明人: Masahiro Eda , Tomoko Kuroda , Keiichi Aritomo , Yoshiyuki Aoki , Satoshi Kaneko
- 申请人： Masahiro Eda , Tomoko Kuroda , Keiichi Aritomo , Yoshiyuki Aoki , Satoshi Kaneko
- 申请人地址： JP Osaka-shi
- 专利权人： MITSUBISHI TANABE PHARMA CORPORATION
- 当前专利权人： MITSUBISHI TANABE PHARMA CORPORATION
- 当前专利权人地址： JP Osaka-shi
- 优先权： JP2007-005472 20070115
- 国际申请： PCT/JP2008/050349 WO 20080115
- 主分类号： A61K31/473
- IPC分类号： A61K31/473 ; C07D221/16 ; C07D413/10 ; C07D401/10 ; C07D471/04 ; C07D487/04 ; A61K31/4741 ; A61K31/4985 ; A61P25/00 ; A61P25/22 ; A61P25/24
摘要：
The problem of the present invention is to provide a compound having a GR selective binding activity, which shows less action on other nuclear receptors such as progesterone receptor (PR), mineralocorticoid receptor (MR) and the like. The present invention provides a condensed tetrahydroquinoline compound represented by the following formula (I) wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof or a hydrate thereof.