发明申请
- 专利标题： Antibodies against human IL17 and uses thereof
- 专利标题（中）： 针对人IL17的抗体及其用途
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申请号： US12586893申请日： 2009-09-29
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公开(公告)号： US20100080812A1公开(公告)日： 2010-04-01
- 发明人: Johannes Auer , Nikolaos Dimoudis , Guy Georges , Petra Hanke , Hendrik Knoetgen , Ekkehard Moessner , Claire Louise Langrish
- 申请人： Johannes Auer , Nikolaos Dimoudis , Guy Georges , Petra Hanke , Hendrik Knoetgen , Ekkehard Moessner , Claire Louise Langrish
- 优先权： EP08017155.6 20080929
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C07H21/00 ; A61P11/06 ; A61P19/02 ; C12N15/63 ; C12P21/00 ; C12N5/00
摘要：
An antibody binding to IL-17 characterized by binding to the same IL-17 epitope to which monoclonal antibody 3C1 binds, and being of human IgG1 isotype modified in the hinge region at amino acid position 216-240, preferably at amino acid position 220-240, between CH1 and CH2 and/or in the second inter-domain region at amino acid position 327-331 between CH2 and CH3 has advantageous properties for the treatment of inflammatory diseases.
公开/授权文献
- US08003099B2 Antibodies against human IL17 and uses thereof 公开/授权日：2011-08-23
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