发明申请
- 专利标题： THERAPEUTIC METHODS USING WRN BINDING MOLECULES
- 专利标题（中）： 使用WRN结合分子的治疗方法
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申请号： US12438793申请日： 2007-08-29
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公开(公告)号： US20100093716A1公开(公告)日： 2010-04-15
- 发明人: Barbara A. Gilchrest , Mark S. Eller , Angela N. Koehler , Olivia M. McPherson , Christopher S. Neumann , Timothy A. Lewis
- 申请人： Barbara A. Gilchrest , Mark S. Eller , Angela N. Koehler , Olivia M. McPherson , Christopher S. Neumann , Timothy A. Lewis
- 申请人地址： US MA Boston
- 专利权人： TRUSTEES OF BOSTON UNIVERSITY AND PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- 当前专利权人： TRUSTEES OF BOSTON UNIVERSITY AND PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- 当前专利权人地址： US MA Boston
- 国际申请： PCT/US07/77147 WO 20070829
- 主分类号： A61K31/5386
- IPC分类号： A61K31/5386 ; C07D498/20 ; A61P35/04
摘要：
The present invention provides, inter alia, compositions and methods for treating various diseases and disorders in a mammal by administering to a mammal in need an effective amount of a composition comprising a non-DNA small molecule that binds WRN, such as members of the spirooxindole (SPOX) class.
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