发明申请
US20100098713A1 NOVEL 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 AND 65577 MOLECULES AND USES THEREFOR
失效
新颖的27877,18080,14081,32140,50352,16658,14223,16002,50566,655552和65577分子及其用途
- 专利标题: NOVEL 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 AND 65577 MOLECULES AND USES THEREFOR
- 专利标题(中): 新颖的27877,18080,14081,32140,50352,16658,14223,16002,50566,655552和65577分子及其用途
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申请号: US12559673申请日: 2009-09-15
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公开(公告)号: US20100098713A1公开(公告)日: 2010-04-22
- 发明人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Welch , Rajasekhar Bandaru
- 申请人: Rachel E. Meyers , Joseph M. Carroll , William James Cook , Rosana Kapeller-Libermann , Nadine S. Welch , Rajasekhar Bandaru
- 申请人地址: US MA Cambridge
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07H21/00 ; C12N1/00 ; C12N5/00 ; C07K14/00 ; C07K16/00 ; C12P21/00 ; G01N33/53 ; G01N33/48 ; G01N33/68 ; A61K38/02 ; A61K38/16 ; A61K31/7052 ; A61P35/00 ; A61P25/00 ; A61P7/00 ; A61P19/00 ; A61P21/00 ; A61P9/00
摘要:
The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 gene has been introduced or disrupted. The invention still further provides isolated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 proteins, fusion proteins, antigenic peptides and anti-27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 or 65577 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.