发明申请
US20100125062A1 PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS
有权
吡啶和吡嗪衍生物作为磷酸二酯酶10抑制剂
- 专利标题： PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS
- 专利标题（中）： 吡啶和吡嗪衍生物作为磷酸二酯酶10抑制剂
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申请号： US12619573申请日： 2009-11-16
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公开(公告)号： US20100125062A1公开(公告)日： 2010-05-20
- 发明人: Jennifer R. Allen , Kaustav Biswas , Frank Chavez, Jr. , Ning Chen , Frenel Fils Demorin , James R. Falsey , Mike Frohn , Paul Harrington , Dan Horne , Essa Hu , Matthew R. Kaller , Roxanne Kunz , Holger Monenschein , Tom Nguyen , Alex Pickrell , Andreas Reichelt , Shannon Rumfelt , Rob Rzasa , Kelvin Sham , Guomin Yao
- 申请人： Jennifer R. Allen , Kaustav Biswas , Frank Chavez, Jr. , Ning Chen , Frenel Fils Demorin , James R. Falsey , Mike Frohn , Paul Harrington , Dan Horne , Essa Hu , Matthew R. Kaller , Roxanne Kunz , Holger Monenschein , Tom Nguyen , Alex Pickrell , Andreas Reichelt , Shannon Rumfelt , Rob Rzasa , Kelvin Sham , Guomin Yao
- 申请人地址： US CA Thousand Oaks
- 专利权人： AMEN INC.
- 当前专利权人： AMEN INC.
- 当前专利权人地址： US CA Thousand Oaks
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; C07D401/12 ; C07D471/04 ; C07D473/00 ; C07D413/14 ; C07D401/14 ; A61K31/437 ; A61K31/52 ; A61K31/5377 ; A61K31/55 ; A61K31/397 ; A61P25/00
摘要：
Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.