发明申请
US20100150872A1 POLYPEPTIDES DERIVED FROM THE HEMOPEXIN-LIKE DOMAIN OF METALLOPROTEINASE MMP-2
审中-公开
衍生自金属蛋白酶MMP-2的HEMOPEXIN-like域的多肽
- 专利标题： POLYPEPTIDES DERIVED FROM THE HEMOPEXIN-LIKE DOMAIN OF METALLOPROTEINASE MMP-2
- 专利标题（中）： 衍生自金属蛋白酶MMP-2的HEMOPEXIN-like域的多肽
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申请号： US12302690申请日： 2007-05-30
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公开(公告)号： US20100150872A1公开(公告)日： 2010-06-17
- 发明人: Andreas Bikfalvi , Carlo Sala , Lorenzo Bello
- 申请人： Andreas Bikfalvi , Carlo Sala , Lorenzo Bello
- 优先权： EP06290892.6 20060601
- 国际申请： PCT/IB07/01413 WO 20070530
- 主分类号： A61K38/46
- IPC分类号： A61K38/46 ; C12N9/50 ; C12N9/96 ; C12N15/57 ; C12N15/63 ; C12N5/00 ; A61K31/7052 ; A61K35/12 ; A61P35/00 ; A61P19/02 ; A61P3/10 ; A61P17/06 ; A61P17/00 ; A61P29/00
摘要：
The present invention relates to anti-angiogenic polypeptides derived from the non catalytic C-terminal hemopexin-like domain of the metalloproteinase MMP-2. The invention also provides pharmaceutical compositions comprising said anti-angiogenic polypeptides and methods for using said polypeptide for treating angiogenic diseases, and in particular for treating cancer.
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