发明申请
- 专利标题： SHEET FOR GUIDING REGENERATION OF MESENCHYMAL TISSUE AND PRODUCTION METHOD THEREOF
- 专利标题（中）： 引导生殖组织再生及其生产方法的论文
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申请号： US12709748申请日： 2010-02-22
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公开(公告)号： US20100158982A1公开(公告)日： 2010-06-24
- 发明人: Toshitsugu KAWATA , Kaoru Tenjo , Koichiro Tsuji , Katsuyuki Yamanaka
- 申请人： Toshitsugu KAWATA , Kaoru Tenjo , Koichiro Tsuji , Katsuyuki Yamanaka
- 申请人地址： JP Tokyo JP Hiroshima-shi
- 专利权人： GC CORPORATION,TWO CELLS Co., Ltd.
- 当前专利权人： GC CORPORATION,TWO CELLS Co., Ltd.
- 当前专利权人地址： JP Tokyo JP Hiroshima-shi
- 优先权： JP2004-309878 20041025
- 主分类号： A61K35/28
- IPC分类号： A61K35/28 ; A61K9/70 ; A61P19/00 ; A61P21/00
摘要：
To provide a sheet for guiding regeneration of mesenchymal tissue having improved formability, strength, absorbability and efficiency, the sheet is produced by steps of containing a culture medium in a surface of a porous sheet produced by freezing a bioabsorbable polymer material dissolved with an organic solvent and drying it, seeding a mesenchymal cell grown after taking from biotissue, and differentiating the mesenchymal cell to a mesenchymal tissue precursor cell, where the mesenchymal tissue precursor cell and an extracellular substrate are adhered on the surface of the porous sheet containing a culture medium, and the extracellular substrate is secreted in a process of the mesenchymal cell being differentiated to the mesenchymal tissue precursor cell.
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