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1.发明申请SHEET FOR GUIDING REGENERATION OF MESENCHYMAL TISSUE AND PRODUCTION METHOD THEREOF 有权引导生殖组织再生及其生产方法的论文公开(公告)号：US20100158982A1
公开(公告)日：2010-06-24
申请号：US12709748
申请日：2010-02-22
CPC分类号： A61L27/3804 , A61F2/2846 , A61F2/3094 , A61F2002/30062 , A61F2210/0004 , A61K35/35 , A61K2035/124 , A61L27/3633 , A61L27/3641 , A61L27/3839 , A61L31/005 , C12N5/0663 , C12N2533/40
摘要： To provide a sheet for guiding regeneration of mesenchymal tissue having improved formability, strength, absorbability and efficiency, the sheet is produced by steps of containing a culture medium in a surface of a porous sheet produced by freezing a bioabsorbable polymer material dissolved with an organic solvent and drying it, seeding a mesenchymal cell grown after taking from biotissue, and differentiating the mesenchymal cell to a mesenchymal tissue precursor cell, where the mesenchymal tissue precursor cell and an extracellular substrate are adhered on the surface of the porous sheet containing a culture medium, and the extracellular substrate is secreted in a process of the mesenchymal cell being differentiated to the mesenchymal tissue precursor cell.
摘要翻译： 为了提供一种用于引导具有改善的成形性，强度，吸收性和效率的间充质组织再生的片材，该片材通过以下步骤制备：在通过冷冻溶解有有机溶剂的生物可吸收聚合物材料制成的多孔片材的表面中含有培养基 并将其干燥，接种从生物组织取出后生长的间充质细胞，并将间充质细胞分化为间充质组织前体细胞，其中间充质组织前体细胞和细胞外基质粘附在含有培养基的多孔片材的表面上， 并且细胞外基质在分化成间充质组织前体细胞的间充质细胞的过程中分泌。
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2.发明申请SHEET FOR GUIDING REGENERATION OF MESENCHYMAL TISSUE AND PRODUCTION METHOD THEREOF 审中-公开引导生殖组织再生及其生产方法的论文公开(公告)号：US20080220521A1
公开(公告)日：2008-09-11
申请号：US12123572
申请日：2008-05-20
IPC分类号： C12N5/02
CPC分类号： A61L27/3804 , A61F2/2846 , A61F2/3094 , A61F2002/30062 , A61F2210/0004 , A61K35/35 , A61K2035/124 , A61L27/3633 , A61L27/3641 , A61L27/3839 , A61L31/005 , C12N5/0663 , C12N2533/40
摘要： To provide a sheet for guiding regeneration of mesenchymal tissue having improved formability, strength, absorbability and efficiency, the sheet is produced by steps of containing a culture medium in a surface of a porous sheet produced by freezing a bioabsorbable polymer material dissolved with an organic solvent and drying it, seeding a mesenchymal cell grown after taking from biotissue, and differentiating the mesenchymal cell to a mesenchymal tissue precursor cell, where the mesenchymal tissue precursor cell and an extracellular substrate are adhered on the surface of the porous sheet containing a culture medium, and the extracellular substrate is secreted in a process of the mesenchymal cell being differentiated to the mesenchymal tissue precursor cell.
摘要翻译： 为了提供一种用于引导具有改善的成形性，强度，吸收性和效率的间充质组织再生的片材，该片材通过以下步骤制备：在通过冷冻溶解有有机溶剂的生物可吸收聚合物材料制成的多孔片材的表面中含有培养基 并将其干燥，接种从生物组织取出后生长的间充质细胞，并将间充质细胞分化为间充质组织前体细胞，其中间充质组织前体细胞和细胞外基质粘附在含有培养基的多孔片材的表面上， 并且细胞外基质在分化成间充质组织前体细胞的间充质细胞的过程中分泌。
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3.发明授权Sheet for guiding regeneration of mesenchymal tissue and production method thereof 有权用于引导间充质组织再生的片材及其制造方法公开(公告)号：US08722404B2
公开(公告)日：2014-05-13
申请号：US12709748
申请日：2010-02-22
IPC分类号： C12N5/077 , C12N5/0789 , C12N5/0797 , C12N5/02 , A61F2/00 , A61F2/02
CPC分类号： A61L27/3804 , A61F2/2846 , A61F2/3094 , A61F2002/30062 , A61F2210/0004 , A61K35/35 , A61K2035/124 , A61L27/3633 , A61L27/3641 , A61L27/3839 , A61L31/005 , C12N5/0663 , C12N2533/40
摘要： Method for regeneration of mesenchymal tissue from mesenchymal cells on a porous sheet composed of bioabsorbable polymer material.
摘要翻译： 从由生物可吸收聚合物材料组成的多孔片材上的间充质细胞的间充质组织的再生方法。
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4.发明申请Sheet for guiding regeneration of mesenchymal tissue and production method thereof 审中-公开用于引导间充质组织再生的片材及其制造方法公开(公告)号：US20060088569A1
公开(公告)日：2006-04-27
申请号：US11256107
申请日：2005-10-24
IPC分类号： A61F13/00
CPC分类号： A61L27/3804 , A61F2/2846 , A61F2/3094 , A61F2002/30062 , A61F2210/0004 , A61K35/35 , A61K2035/124 , A61L27/3633 , A61L27/3641 , A61L27/3839 , A61L31/005 , C12N5/0663 , C12N2533/40
摘要： To provide a sheet for guiding regeneration of mesenchymal tissue having improved formability, strength, absorbability and efficiency, the sheet is produced by steps of containing a culture medium in a surface of a porous sheet produced by freezing a bioabsorbable polymer material dissolved with an organic solvent and drying it, seeding a mesenchymal cell grown after taking from biotissue, and differentiating the mesenchymal cell to a mesenchymal tissue precursor cell, where the mesenchymal tissue precursor cell and an extracellular substrate are adhered on the surface of the porous sheet containing a culture medium, and the extracellular substrate is secreted in a process of the mesenchymal cell being differentiated to the mesenchymal tissue precursor cell.
摘要翻译： 为了提供一种用于引导具有改善的成形性，强度，吸收性和效率的间充质组织再生的片材，该片材通过以下步骤制备：在通过冷冻溶解有有机溶剂的生物可吸收聚合物材料制成的多孔片材的表面中含有培养基 并将其干燥，接种从生物组织取出后生长的间充质细胞，并将间充质细胞分化为间充质组织前体细胞，其中间充质组织前体细胞和细胞外基质粘附在含有培养基的多孔片材的表面上， 并且细胞外基质在分化成间充质组织前体细胞的间充质细胞的过程中分泌。
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