Invention Application
US20100173886A1 BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
失效
用于治疗代谢性疾病的双相ARYL和HETEROARYL化合物
- Patent Title: BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
- Patent Title (中): 用于治疗代谢性疾病的双相ARYL和HETEROARYL化合物
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Application No.: US12601100Application Date: 2008-05-22
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Publication No.: US20100173886A1Publication Date: 2010-07-08
- Inventor: Jason Bloxham , Stuart Edward Bradley , Tom Banksia Dupree , Peter Timothy Fry , Patrick Eric Hanrahan , Thomas Martin Krulle , Martin James Procter , Colin Peter Sambrook-Smith , Karen Lesley Schofield , Donald Smyth , Alan John Stewart
- Applicant: Jason Bloxham , Stuart Edward Bradley , Tom Banksia Dupree , Peter Timothy Fry , Patrick Eric Hanrahan , Thomas Martin Krulle , Martin James Procter , Colin Peter Sambrook-Smith , Karen Lesley Schofield , Donald Smyth , Alan John Stewart
- Priority: GB0709789.2 20070522; GB0800454.1 20080111
- International Application: PCT/GB08/50370 WO 20080522
- Main IPC: A61K31/397
- IPC: A61K31/397 ; C07D213/84 ; A61K31/44 ; C07D217/22 ; A61K31/47 ; C07D403/12 ; A61K31/496 ; C07D413/12 ; A61K31/5377 ; A61P3/10 ; A61P9/12 ; A61P25/24 ; A61P25/32 ; A61P25/36
Abstract:
Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.
Public/Granted literature
- US08278442B2 Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders Public/Granted day:2012-10-02
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