发明申请
US20100173928A1 Phosphorylation and regulation of AKT/PKB by the rictor-mTOR complex
审中-公开
通过rictor-mTOR复合物的AKT / PKB的磷酸化和调节
- 专利标题： Phosphorylation and regulation of AKT/PKB by the rictor-mTOR complex
- 专利标题（中）： 通过rictor-mTOR复合物的AKT / PKB的磷酸化和调节
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申请号： US12218629申请日： 2008-07-15
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公开(公告)号： US20100173928A1公开(公告)日： 2010-07-08
- 发明人: David M. Sabatini , Dos D. Sarbassov , Michael Andreeff , Marina Konopleva , Zhihong Zeng , Francis J. Giles
- 申请人： David M. Sabatini , Dos D. Sarbassov , Michael Andreeff , Marina Konopleva , Zhihong Zeng , Francis J. Giles
- 主分类号： A61K31/436
- IPC分类号： A61K31/436 ; C12N5/00 ; C12Q1/02 ; A61P35/00
摘要：
In certain aspects, the invention relates to methods for identifying compounds which modulate Akt activity mediated by the rictor-mTOR complex and methods for treating or preventing a disorder that is associated with aberrant Akt activity.
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