Provided is a method for detecting an analyte, wherein the analyte is labelled with one or more labels relatable to the analyte, which method comprises: a) performing an optical detection method on the labelled analyte to obtain optical data from the one or more labels; b) performing an electrical detection method on the labelled analyte to obtain electrical data from the one or more labels; and c) determining the identity and/or quantity of the analyte from both the optical and electrical data. Further provided is a method for detecting a plurality of analytes, wherein the each different analyte is labelled with one or more different labels relatable to the analyte, which method comprises: a) performing an optical detection method on a plurality of labelled analytes to obtain optical data from the labels; b) performing an electrochemical detection method on the plurality of labelled analytes to obtain electrical data from the labels; and c) determining the identity and/or quantity of the plurality of analytes from both the optical and electrical data.