发明申请
- 专利标题： ARYLSULFONAMIDE DERIVATIVES FOR USE AS CCR3 ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DISORDERS
- 专利标题（中）： 用于治疗炎症和免疫疾病的CCR3拮抗剂的磺酰苯胺衍生物
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申请号： US12763072申请日： 2010-04-19
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公开(公告)号： US20100204213A1公开(公告)日： 2010-08-12
- 发明人: Yingfu LI , Akihiko Watanabe , Timothy B. Lowinger , Kevin Bacon , Norihiro Kawamura , Takuya Shintani , Tetsuo Kikuchi , Toshiya Moriwaki , Klaus Urbahns , Keiko Eukushima , Noriko Nunami , Takashi Yoshino , Toshiki Murata , Megumi Yamauchi , Hiroko Yoshino
- 申请人： Yingfu LI , Akihiko Watanabe , Timothy B. Lowinger , Kevin Bacon , Norihiro Kawamura , Takuya Shintani , Tetsuo Kikuchi , Toshiya Moriwaki , Klaus Urbahns , Keiko Eukushima , Noriko Nunami , Takashi Yoshino , Toshiki Murata , Megumi Yamauchi , Hiroko Yoshino
- 优先权： JP2001-272327 20010907
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D241/04 ; A61K31/495 ; C07D403/12 ; A61K31/496 ; C07D243/08 ; A61P25/28 ; A61P19/02 ; A61P11/06 ; A61P9/10 ; A61P31/18 ; A61P11/00
摘要：
The present invention relates to a sulfonamide derivative which is useful as an active ingredient of pharmaceutical preparations. The sulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders.
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