发明申请
- 专利标题： Amino-pyridines As Inhibitors Of Beta-secretase
- 专利标题（中）： 氨基吡啶作为β分泌酶的抑制剂
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申请号： US12763612申请日： 2010-04-20
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公开(公告)号： US20100204245A1公开(公告)日： 2010-08-12
- 发明人: Michael Sotirios Malamas , William Floyd Fobare , William Ronald Solvibile, JR. , Frank Eldridge Lovering , Jeffrey Scott Condon , Albert Jean Robichaud
- 申请人： Michael Sotirios Malamas , William Floyd Fobare , William Ronald Solvibile, JR. , Frank Eldridge Lovering , Jeffrey Scott Condon , Albert Jean Robichaud
- 申请人地址： US NJ Madison
- 专利权人： Wyeth LLC
- 当前专利权人： Wyeth LLC
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D401/06 ; A61K31/4439 ; C07D401/12 ; A61K31/444 ; A61K31/506 ; A61P25/28 ; C12N5/071
摘要：
The present invention provides an amino-pyridine compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.
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