发明申请
- 专利标题: Highly Acidic Chitosan-Nucleic Acid Polyplex Compositions
- 专利标题(中): 高酸性壳聚糖 - 核酸复合组合物
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申请号: US12751572申请日: 2010-03-31
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公开(公告)号: US20100261780A1公开(公告)日: 2010-10-14
- 发明人: Jun GAO , Carlos Fleet , Eric Hsu , Anthony Cheung
- 申请人: Jun GAO , Carlos Fleet , Eric Hsu , Anthony Cheung
- 申请人地址: CA Vancouver
- 专利权人: enGene, Inc.
- 当前专利权人: enGene, Inc.
- 当前专利权人地址: CA Vancouver
- 主分类号: A61K31/7052
- IPC分类号: A61K31/7052 ; C08B37/08 ; C12N15/85 ; A61P29/00 ; A61P11/00
摘要:
The invention provides highly acidic chitosan-nucleic acid polyplex compositions. The compositions may be used to transfect cells in vitro and in vivo, and are particularly useful for transfecting cells of mucosal epithelia.