公开(公告)号：US08722646B2

公开(公告)日：2014-05-13

申请号：US12680527

申请日：2008-09-26

申请人： Eric Hsu ,  Carlos Fleet ,  Anthony Cheung ,  Jun Gao

发明人： Eric Hsu ,  Carlos Fleet ,  Anthony Cheung ,  Jun Gao

IPC分类号： A61K31/722 ,  A61K48/00 ,  C07H21/04

CPC分类号： C08B37/0063 ,  A61K31/7088 ,  C07H17/02 ,  C12N15/87 ,  Y10T428/2982

摘要： The invention provides highly concentrated chitosan-nucleic acid polyplex compositions and dispersions, and methods for producing the compositions and dispersions. Methods of mixing the chitosan-nucleic acid polyplexes include an inline mixing of chitosan solution and nucleic acid solution, followed by further concentrating the dispersion of chitosan-nucleic acid polyplexes, optionally with an aggregation inhibitor. Further provided are methods for altering the diameter of chitosan-nucleic acid polyplexes.

摘要翻译： 本发明提供高度浓缩的壳聚糖 - 核酸复合物组合物和分散体，以及用于制备组合物和分散体的方法。 混合壳聚糖 - 核酸复合物的方法包括壳聚糖溶液和核酸溶液的在线混合，随后进一步浓缩壳聚糖 - 核酸复合物的分散体，任选地与聚集抑制剂。 还提供了改变壳聚糖 - 核酸复合物直径的方法。

公开(公告)号：US20100261780A1

公开(公告)日：2010-10-14

申请号：US12751572

申请日：2010-03-31

申请人： Jun GAO ,  Carlos Fleet ,  Eric Hsu ,  Anthony Cheung

发明人： Jun GAO ,  Carlos Fleet ,  Eric Hsu ,  Anthony Cheung

IPC分类号： A61K31/7052 ,  C08B37/08 ,  C12N15/85 ,  A61P29/00 ,  A61P11/00

CPC分类号： C12N15/87 ,  A61K47/61 ,  A61K48/0041

摘要： The invention provides highly acidic chitosan-nucleic acid polyplex compositions. The compositions may be used to transfect cells in vitro and in vivo, and are particularly useful for transfecting cells of mucosal epithelia.

摘要翻译： 本发明提供了高度酸性的壳聚糖 - 核酸复合物组合物。 组合物可用于体外和体内转染细胞，并且特别可用于转染粘膜上皮细胞。

公开(公告)号：US20050202559A1

公开(公告)日：2005-09-15

申请号：US10697700

申请日：2003-10-29

申请人： Scott Pownall ,  Anthony Cheung ,  Eric Hsu ,  Bruno Doiron

发明人： Scott Pownall ,  Anthony Cheung ,  Eric Hsu ,  Bruno Doiron

IPC分类号： A61K45/06 ,  A61P35/00 ,  C12N15/85 ,  C12P19/04 ,  G01N33/50

CPC分类号： A61K38/45 ,  A61K38/47 ,  A61K45/06 ,  A61K48/005 ,  C12N9/16 ,  C12N15/86 ,  C12N2710/10343 ,  C12Q1/25 ,  C12Q1/34 ,  C12Y301/03016 ,  G01N33/5011 ,  G01N33/5023

摘要： The invention provides compositions and methods for inhibiting the growth or proliferation of hyperproliferative cells or inducing regression of hyperproliferative cells. More specifically, the invention provides compositions and methods for stimulating glycogen accumulation in target cells (e.g., hyperproliferative cells) in order to increase glycogen to a level that is toxic to the target cell.

摘要翻译： 本发明提供了抑制过度增殖细胞生长或增殖或诱导过度增殖细胞退化的组合物和方法。 更具体地，本发明提供了用于刺激靶细胞（例如，过度增殖细胞）中的糖原积累的组合物和方法，以便将糖原增加至对靶细胞有毒性的水平。

公开(公告)号：US20070037669A1

公开(公告)日：2007-02-15

申请号：US11228837

申请日：2005-09-16

申请人： Eric Hsu

发明人： Eric Hsu

IPC分类号： A63B22/04

CPC分类号： A63B22/0664 ,  A63B21/225 ,  A63B22/001 ,  A63B22/0046 ,  A63B2022/067 ,  A63B2071/025

摘要： An elliptical exercise device includes a main frame having a rotary shaft defining an axis, left and right link rods having rear ends connected to the rotary shaft for rotation about the axis, left and right arms connected respectively to front ends of the link rods for reciprocal movement, and left and right foot plates connected pivotally and respectively to the link rods and movable along elliptical paths when the rear ends of the link rods rotate. A guide mechanism is connected to the foot plates and the main frame to restrict movement of the foot plates. Each foot plate is substantially horizontal when moving upward or downward from the lowest or highest point of the corresponding elliptical path.

摘要翻译： 椭圆运动装置包括具有限定轴线的旋转轴的主框架，左连杆和右连杆具有连接到旋转轴的后端，用于围绕轴线旋转，左右臂分别连接到连杆的前端用于往复运动 运动以及左右脚板可枢转地分别连接到连杆上，并且当连杆的后端旋转时可沿着椭圆形路径移动。 引导机构连接到脚板和主框架以限制脚板的运动。 当从对应的椭圆路径的最低点或最高点向上或向下移动时，每个脚踏板基本上是水平的。

公开(公告)号：US08988354B2

公开(公告)日：2015-03-24

申请号：US13449220

申请日：2012-04-17

申请人： Richard Milhe ,  Tarak Fekih ,  Alexis Richard ,  Sylvain Sauvage ,  Laurent Plancherel ,  Pai-Cheng Chu ,  Eric Hsu

发明人： Richard Milhe ,  Tarak Fekih ,  Alexis Richard ,  Sylvain Sauvage ,  Laurent Plancherel ,  Pai-Cheng Chu ,  Eric Hsu

IPC分类号： G06F3/02 ,  G06F1/16

CPC分类号： G06F1/1671 ,  G06F1/1677 ,  G06F1/3271 ,  Y02D10/156

摘要： Embodiments of the invention are directed to an input device comprising a processor configured to operate the input device in one of a plurality of modes of operation, a plurality of buttons, and a housing configured to receive and secure a display device. The housing is configurable in a plurality of positions relative to the plurality of buttons, where at least a portion of the plurality of buttons operates in one of the plurality of modes of operation based, at least in part, on a position of the plurality of positions of the housing relative to the plurality of buttons.

摘要翻译： 本发明的实施例涉及一种输入装置，其包括处理器，其被配置为以多种操作模式中的一种操作输入装置，多个按钮和被配置为接收和固定显示装置的壳体。 壳体可配置成相对于多个按钮的多个位置，其中多个按钮的至少一部分基于至少部分地基于多个操作模式的位置而以多种操作模式中的一种操作 壳体相对于多个按钮的位置。

公开(公告)号：US08870477B2

公开(公告)日：2014-10-28

申请号：US12647543

申请日：2009-12-28

申请人： Baptiste Merminod ,  Peter Mah ,  Eric Hsu ,  Aaron Lee ,  Jero Chen ,  Linus Chien ,  Eric Su

发明人： Baptiste Merminod ,  Peter Mah ,  Eric Hsu ,  Aaron Lee ,  Jero Chen ,  Linus Chien ,  Eric Su

IPC分类号： B41J5/12 ,  H01H3/12 ,  H01H13/83 ,  H01H9/18

CPC分类号： H01H3/125 ,  B29C45/16 ,  B29L2031/466 ,  H01H11/00 ,  H01H13/70 ,  H01H13/83 ,  H01H2009/187 ,  H01H2209/052 ,  H01H2219/028 ,  H01H2219/062 ,  H01H2223/002

摘要： A key for a keyboard includes a keycap having a top surface configured to be contacted for pressing the key down, and having a bottom. The keycap is substantially transparent. An intermediate layer is coupled to the bottom of the keycap. The intermediate layer is translucent and includes a top and a bottom. The top of the intermediate layer faces the bottom of the keycap. A character layer is positioned between the bottom of the keycap and the top of the intermediate layer. A resilient member is coupled to the bottom of the intermediate layer. The resilient member is translucent and is configured to direct light through the intermediate layer, through the character layer, and out from the keycap. The character layer is configured to be lighted for viewing through the keycap.

摘要翻译： 键盘的键包括键帽，其具有被配置为接触以压下钥匙的顶表面，并具有底部。 键帽基本上是透明的。 中间层耦合到键帽的底部。 中间层是半透明的并且包括顶部和底部。 中间层的顶部面向键帽的底部。 字符层位于键帽的底部和中间层的顶部之间。 弹性构件联接到中间层的底部。 弹性构件是半透明的，并且被配置成将光引导通过中间层，穿过字符层，并从键帽出来。 字符层被配置为点亮以通过键帽观看。

公开(公告)号：US07958818B2

公开(公告)日：2011-06-14

申请号：US10543272

申请日：2004-01-22

申请人： Eric Hsu

发明人： Eric Hsu

IPC分类号： A23L1/20 ,  A23J3/16

CPC分类号： A23C20/025

摘要： A soy curding apparatus for continuously producing soy curd from soy milk including a pump for pumping soy milk and soy curd; a coagulator dispensing apparatus positioned for adding a coagulant; an expansion chamber to produce a pre soy curd mixture; a maturing apparatus to allow further mixing and maturing of the soy curd; a whey separating apparatus for separating the whey from the curd; a tower to remove residual whey to form a plug of soy curd of a desired consistency and moisture content and to cut a block from the soy plug; a conveyor apparatus adapted to receive and transport the block from the tower.

摘要翻译： 一种用于从豆浆连续生产大豆凝乳的大豆凝固装置，包括用于泵送豆浆和大豆凝乳的泵; 一种用于加入凝结剂的凝结剂分配装置; 膨胀室以产生预大豆凝乳混合物; 一种熟化装置，以进一步混合和熟化大豆凝乳; 用于从凝乳中分离乳清的乳清分离装置; 塔，以除去残留乳清以形成所需稠度和水分含量的大豆凝乳塞，并从大豆塞切割块; 输送装置，适于从塔架接收和运输块体。

公开(公告)号：US20090069158A1

公开(公告)日：2009-03-12

申请号：US12025105

申请日：2008-02-04

申请人： Eric Hsu

发明人： Eric Hsu

IPC分类号： A63B69/16

CPC分类号： A63B22/0664 ,  A63B21/225 ,  A63B22/001 ,  A63B2022/067

摘要： An elliptical exercising device includes a rotating unit mounted on a support frame, and two link rods connected to the rotating unit such that intermediate segments of the link rods are moved reciprocatively in an elliptical path. A foot support is tiltably mounted on the intermediate segment. A suspending rail is moved with the foot support to be subjected to a gradually varying urging force resulting from movement of the intermediate segment and to be continuously urged to angularly move. A rail engaging rider slidably contacts the suspending rail to be urged by the urging force to angularly move upwards or downwards. An urging force counteracting mechanism is mounted pivotally on the support frame, and is coupled with the rail engaging rider so as to impart a force to counteract an x-axis force component of the urging force to thereby keep the suspending rail in a horizontal position.

摘要翻译： 椭圆运动装置包括安装在支撑框架上的旋转单元和连接到旋转单元的两个连杆，使得连杆的中间段在椭圆路径中往复运动。 脚支撑可倾斜地安装在中间段上。 悬挂轨道随着脚部支撑件移动以经受由中间段的运动产生的逐渐变化的推动力，并且被连续地推动成角度地移动。 轨道接合骑手可滑动地接触悬挂轨道，以被推动力推动以向上或向下成角度地移动。 推力反作用机构枢转地安装在支撑框架上，并且与轨道接合骑手联接，以便施加力以抵消推动力的x轴力分力，从而将悬挂轨道保持在水平位置。

公开(公告)号：US07226391B2

公开(公告)日：2007-06-05

申请号：US11228837

申请日：2005-09-16

申请人： Eric Hsu

发明人： Eric Hsu

IPC分类号： A63B22/00

CPC分类号： A63B22/0664 ,  A63B21/225 ,  A63B22/001 ,  A63B22/0046 ,  A63B2022/067 ,  A63B2071/025

摘要： An elliptical exercise device includes a main frame having a rotary shaft defining an axis, left and right link rods having rear ends connected to the rotary shaft for rotation about the axis, left and right arms connected respectively to front ends of the link rods for reciprocal movement, and left and right foot plates connected pivotally and respectively to the link rods and movable along elliptical paths when the rear ends of the link rods rotate. A guide mechanism is connected to the foot plates and the main frame to restrict movement of the foot plates. Each foot plate is substantially horizontal when moving upward or downward from the lowest or highest point of the corresponding elliptical path.

公开(公告)号：US20060133191A1

公开(公告)日：2006-06-22

申请号：US10543272

申请日：2004-01-22

申请人： Eric Hsu

发明人： Eric Hsu

IPC分类号： B01F15/00

CPC分类号： A23C20/025

摘要： A soy curding apparatus for continuously producing soy curd from soy milk including a pump for pumping soy milk and soy curd; a coagulator dispensing means positioned for adding a coagulant; an expansion chamber to produce a pre-soy curd mixture; a maturing means to allow further mixing and maturing of the soy curd; a whey separating means for separating the whey from the curd; a tower to remove residual whey to form a plug of soy curd of a desired consistency and moisture content and to cut a block from the soy plug; a conveyor means adapted to receive and transport the block from the tower.

摘要翻译： 一种用于从豆浆连续生产大豆凝乳的大豆凝固装置，包括用于泵送豆浆和大豆凝乳的泵; 凝结剂分配装置，用于添加凝结剂; 膨胀室以产生大豆前凝乳混合物; 一种成熟的手段，可以进一步混合和熟化大豆凝乳; 用于从凝乳中分离乳清的乳清分离装置; 塔，以除去残留的乳清以形成所需稠度和水分含量的大豆凝乳塞，并从大豆塞切割块; 适于从塔架接收和运输块的传送装置。