Invention Application
US20100292244A1 HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS AKT PROTEIN KINASE INHIBITOR
有权
羟丙基吡咯烷酮作为AKT蛋白激酶抑制剂
- Patent Title: HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS AKT PROTEIN KINASE INHIBITOR
- Patent Title (中): 羟丙基吡咯烷酮作为AKT蛋白激酶抑制剂
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Application No.: US12811983Application Date: 2009-01-09
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Publication No.: US20100292244A1Publication Date: 2010-11-18
- Inventor: Josef Bencsik , James F. Blake , Nicholas C. Kallan , Ian S. Mtchell , Keith L. Spencer , Dengming Xiao , Rui Xu , Christine Chabot , Steven Do , Jun Liang , Brian Safina , Birong Zhang
- Applicant: Josef Bencsik , James F. Blake , Nicholas C. Kallan , Ian S. Mtchell , Keith L. Spencer , Dengming Xiao , Rui Xu , Christine Chabot , Steven Do , Jun Liang , Brian Safina , Birong Zhang
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- International Application: PCT/US09/30602 WO 20090109
- Main IPC: A61K31/517
- IPC: A61K31/517 ; C07D403/04 ; A61P29/00 ; A61P35/00 ; A61P9/00 ; A61P25/00 ; A61P17/00 ; A61P15/02
Abstract:
The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I. Also provided are methods of using the compound of this invention as an AKT protein kinase inhibitor and for the treatment of hyperproliferative diseases such as cancer.
Public/Granted literature
- US08853216B2 Hydroxylated pyrimidyl cyclopentane as AKT protein kinase inhibitor Public/Granted day:2014-10-07
Information query
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