发明申请
- 专利标题： Methods for the early diagnosis of ovarian cancer
- 专利标题（中）： 卵巢癌早期诊断方法
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申请号： US12807390申请日： 2010-09-03
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公开(公告)号： US20110086056A1公开(公告)日： 2011-04-14
- 发明人: Timothy J. O'Brien , Martin J. Cannon , Alessandro Santin , John Beard , Kazushi Shigemasa
- 申请人： Timothy J. O'Brien , Martin J. Cannon , Alessandro Santin , John Beard , Kazushi Shigemasa
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C12N15/57 ; C12N9/48 ; A61K35/12 ; C12Q1/02 ; C12N5/00 ; A61P35/00 ; A61P37/04
摘要：
The present invention discloses the protease hepsin is specifically over-expressed in ovarian and other malignancies. A number of hepsin peptides can induce immune responses to hepsin, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies. There is also provided a hepsin protein variant that is useful as a marker for ovarian cancer cells, prostate cancer cells or kidney cancer cells.
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