发明申请
- 专利标题： MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF
- 专利标题（中）： 咪唑啉酮类似物，合成方法及其用途
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申请号： US12681052申请日： 2008-10-03
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公开(公告)号： US20110136759A1公开(公告)日： 2011-06-09
- 发明人: Daniel Kahne , Suzanne Kahne Walker , Masaatsu Adachi , Emma Doud , Shinichiro Fuse , Xiaonan Lin , Yi Zhang , Hirokazu Tsukamoto , Bohdan Ostash
- 申请人： Daniel Kahne , Suzanne Kahne Walker , Masaatsu Adachi , Emma Doud , Shinichiro Fuse , Xiaonan Lin , Yi Zhang , Hirokazu Tsukamoto , Bohdan Ostash
- 国际申请： PCT/US08/78771 WO 20081003
- 主分类号： A61K31/7024
- IPC分类号： A61K31/7024 ; C07H13/00 ; C12P19/26 ; A61P31/04
摘要：
The present invention provides novel moenomycin analogs as well as pharmaceutical compositions thereof, methods of synthesis, and methods of use in treating an infection by administering an inventive compound to a subject in need thereof. The moenomycin analogs may be prepared synthetically, biosynthetically, or semi-synthetically. The analogs are particularly useful in treating or preventing infections caused by Gram-positive organisms. Certain inventive compounds may have a broader spectrum of coverage, which includes Gram-negative organisms.
公开/授权文献
- US08604004B2 Moenomycin analogs, methods of synthesis, and uses thereof 公开/授权日：2013-12-10
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