Invention Application
- Patent Title: 2-Aminopyrimidine modulators of the histamine H4 receptor
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Application No.: US13043420Application Date: 2011-03-08
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Publication No.: US20110160452A1Publication Date: 2011-06-30
- Inventor: Hui Cai , Frank Chavez , James P. Edwards , Anne E. Fitzgerald , Jing Liu , Neelakandha S. Mani , Danielle K. Neff , Michele C. Rizzolio , Brad M. Savall , Deborah M. Smith , Jennifer D. Venable , Jianmai Wei , Ronald L. Wolin
- Applicant: Hui Cai , Frank Chavez , James P. Edwards , Anne E. Fitzgerald , Jing Liu , Neelakandha S. Mani , Danielle K. Neff , Michele C. Rizzolio , Brad M. Savall , Deborah M. Smith , Jennifer D. Venable , Jianmai Wei , Ronald L. Wolin
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D401/04 ; C07D403/14 ; C07D498/04
Abstract:
2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
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