Invention Application
- Patent Title: GPCR crystalization method using an antibody
- Patent Title (中): 使用抗体的GPCR结晶方法
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Application No.: US12931528Application Date: 2011-02-02
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Publication No.: US20110166330A1Publication Date: 2011-07-07
- Inventor: Brian Kobilka , Daniel Rohrer , Peter Brams , Asna Masood
- Applicant: Brian Kobilka , Daniel Rohrer , Peter Brams , Asna Masood
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
An antibody that specifically binds a three dimensional epitope on the IC3 loop of a GPCR is provided. The antibody may be employed in a method that comprises: contacting a GPCR with a monovalent version of the antibody binding conditions to form a complex; and crystallizing the complex.
Information query
