发明申请
- 专利标题: Synthetic Peptide (Meth) Acrylate Microcarriers
- 专利标题(中): 合成肽(甲基)丙烯酸酯微载体
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申请号: US13028635申请日: 2011-02-16
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公开(公告)号: US20110207216A1公开(公告)日: 2011-08-25
- 发明人: Arthur Winston Martin , Kevin Robert McCarthy , Shawn Michael O'Malley , Simon Kelly Shannon , Meenal Pauddar Soni
- 申请人: Arthur Winston Martin , Kevin Robert McCarthy , Shawn Michael O'Malley , Simon Kelly Shannon , Meenal Pauddar Soni
- 主分类号: C12N5/0775
- IPC分类号: C12N5/0775
摘要:
A process for forming microcarriers includes contacting an initiator-conjugated microcarrier base with one or more monomers and activating the initiator to initiate polymerization and to graft a polymer from the base via the initiator or a remnant thereof. At least one of the monomers is conjugated to a polypeptide so that incorporation of the monomer into the forming polymer conjugates the polypeptide to the polymeric coating as it is formed in situ.
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