发明申请
- 专利标题: GBS Toxin Receptor Compositions and Methods of Use
- 专利标题(中): GBS毒素受体组合物及使用方法
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申请号: US13022357申请日: 2011-02-07
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公开(公告)号: US20110217316A1公开(公告)日: 2011-09-08
- 发明人: Carl G. Hellerqvist , Changlin Fu
- 申请人: Carl G. Hellerqvist , Changlin Fu
- 申请人地址: US TN Nashville
- 专利权人: Vanderbilt University
- 当前专利权人: Vanderbilt University
- 当前专利权人地址: US TN Nashville
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K14/00 ; C07H21/04 ; C07K16/00 ; A61K39/00 ; A61K31/7088 ; A61P35/00 ; A61P37/04 ; G01N33/566 ; C12Q1/02 ; G01N33/567
摘要:
Methods are provided for preventing or attenuating pathoangiogenic conditions by administering at least one GBS toxin receptor polypeptide or at least one immunogenic fragment thereof. Also provided are a composition that includes a GBS toxin receptor polypeptide and a method for making such a composition. In another embodiment of the invention, immunized animals also receive GBS toxin, immunocompatible antibodies to the GBS toxin receptor, and/or expanded autologous T cells to the GBS toxin receptor. Also included in this invention are methods of identifying additional GBS toxin receptors.
公开/授权文献
- US08609614B2 GBS toxin receptor compositions and methods of use 公开/授权日:2013-12-17
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