- 专利标题: GLUCAGON ANALOGUES
-
申请号: US13139487申请日: 2008-12-15
-
公开(公告)号: US20110286981A1公开(公告)日: 2011-11-24
- 发明人: Eddi Meier , Ditte Riber , Marie Skovgaard , Bjarne Due Larsen , Jens Rosengren Daugaard , Trine Skovlund Ryge Neerup
- 申请人: Eddi Meier , Ditte Riber , Marie Skovgaard , Bjarne Due Larsen , Jens Rosengren Daugaard , Trine Skovlund Ryge Neerup
- 申请人地址: DK Glostrup
- 专利权人: Zealand Pharma A/S
- 当前专利权人: Zealand Pharma A/S
- 当前专利权人地址: DK Glostrup
- 国际申请: PCT/GB2008/004157 WO 20081215
- 主分类号: A61K38/26
- IPC分类号: A61K38/26 ; C07H21/00 ; C12N15/63 ; C12N1/21 ; C12N1/19 ; C12N1/11 ; C12N5/10 ; C12N1/15 ; A61K31/7088 ; A61K48/00 ; A61K35/74 ; A61K35/68 ; A61K36/06 ; A61K35/64 ; A61K35/12 ; A61K36/064 ; A61K36/00 ; A61P9/10 ; A61P3/10 ; A61P9/12 ; A61P3/04 ; A61P9/00 ; A61P3/06 ; A61P29/00 ; A61P1/16 ; C07K14/605
摘要:
The invention provides materials and methods for promoting weight loss or preventing weight gain, and in the treatment of diabetes, metabolic syndrome and associated disorders. In particular, the invention provides novel glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.
公开/授权文献
- US08680049B2 Glucagon analogues 公开/授权日:2014-03-25